TCR Identity Assay Development via NGS in Personalized TCR T Cell Product
Time: 2:15 pm
day: Day 1, Track B- PM
Details:
- Multiple TCR sequences will be transfected into ex-vivo cultured T cells per patient to maximise the clinical efficacy
- Drug products contain T cells with multiple engineered TCR sequences.
- NGS method has been explored for TCR identity and qualified to enable it as a release assay for mixed TCR drug product
