Overcoming Challenges in Characterization of Scaled-Up Cell Therapy Products
Time: 5:00 pm
day: Conference Day Two Afternoon
Details:
- Explore strategies for ensuring consistency in product quality and characteristics as cell therapy production scales up, addressing factors such as variability in raw materials, manufacturing processes, and environmental conditions.
- Discuss innovative approaches to sampling and analytical methods to obtain representative samples from larger volumes and adapt traditional techniques for use at scale, facilitating accurate characterization of scaled-up products.
- Examine the complexities introduced by large-scale cell culture systems, including nutrient and oxygen gradients, shear forces, and cell-cell interactions, and discuss strategies for understanding and mitigating these factors to ensure predictable product behavior and consistent characterization across scales.
