Michael Sadick

Michael Sadick

Company: Precision Bioscience

Job title: Senior Director, CMC Analytical Development


Resetting Expectations for CAR-T Potency Assessment… “Baby, You Can Drive My CAR” 11:30 am

• ‘Full serial dilution curve’ bioassays have been difficult to establish for cell therapy modalities, but they provide critical assessment of potency/relative potency • Target cell cytotoxicity assays may well be more MOA reflective than cytokine release bioassays • This presentation will describe successful utilization of a luciferase-complementation-based cytotoxic assay (Promega HiBiT assay) • Application…Read more

day: Day 2 Track 2 AM

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