Michael Sadick

Company: Precision Biosciences
Job title: Senior Director, CMC Analytical Development
Seminars:
Resetting Expectations for CAR-T Potency Assessment… “Baby, You Can Drive My CAR” 2:30 pm
• ‘Full serial dilution curve’ bioassays have been difficult to establish for cell therapy modalities, but they provide critical assessment of potency/relative potency • Target cell cytotoxicity assays may well be more MOA reflective than cytokine release bioassays • This presentation will describe successful utilization of a luciferase-complementation-based cytotoxic assay (Promega HiBiT assay) • Application…Read more
day: Day Two
Panel Discussion: Assess Novel Technologies for Analytical Development 9:00 am
• Stress the need for higher throughput technologies, with less variability and greater user ease • Regulatory agency guidelines on the use of new technologies • Compare thoughts on ddPCR Vs qPCR … Elisa Vs Ella testingRead more
day: Day Two